Prevalence of chronic hepatitis B virus infection and infrastructure for its diagnosis in Madagascar

WHO developed a global strategy to eliminate hepatitis B by 2030 and set target to treat 80% of people with chronic hepatitis B virus (HBV) infection eligible for antiviral treatment. As a first step to achieve this goal, it is essential to conduct a situation analysis that is fundamental to designing national hepatitis plans. We […]

Genetic structure and gene flow of the flea Xenopsylla cheopis in Madagascar and Mayotte

We genotyped 205 fleas from 12 sites using nine microsatellite markers. Madagascan populations of X. cheopis differed, with the mean number of alleles per locus per population ranging from 1.78 to 4.44 and with moderate to high levels of genetic differentiation between populations. Three distinct genetic clusters were identified, with different geographical distributions but with […]

Review of Antibiotic Resistance in the Indian Ocean Commission

Review of Antibiotic Resistance in the Indian Ocean Commission: A Human and Animal Health Issue Noellie Gay1*, Olivier Belmonte2, Jean-Marc Collard3, Mohamed Halifa4, Mohammad Iqbal Issack5, Saindou Mindjae6, Philippe Palmyre7, Abdul Aziz Ibrahim7, Harena Rasamoelina8, Loïc Flachet8, Laurent Filleul9 and Eric Cardinale1,8 Antimicrobial resistance (AMR) is a major threat to human, animal health, and environment […]

Seasonal determinants of access to care: implications for measles outbreak risk in Madagascar

Measles containing vaccine was introduced to Madagascar in 1985. Since 2007, intensification of efforts has bought Madagascar closer to the goal of elimination. Nevertheless, recent data also indicate that population immunity might be eroding in the face of high birth rates and barriers to vaccine delivery. Despite evidence that many factors likely to shape vaccination […]

Evaluation of the influenza sentinel surveillance system in Madagascar, 2009–2014

The World Health Organization (WHO) recommends that, from no more than two years after implementation, influenza surveillance systems should be periodically and comprehensively evaluated.1 Such evaluations may enable shortfalls to be identified, performance to be improved and data reliability to be assessed. Although several influenza surveillance systems have been established in Africa,2,3 data on the […]

Usefulness and accuracy of MALDI-TOF mass spectrometry as a supplementary tool to identify mosquito vector species …

Arthropod-borne diseases are important causes of morbidity and mortality. The identification of vector species relies mainly on morphological features and/or molecular biology tools. The first method requires specific technical skills and may result in misidentifications, and the second method is time-consuming and expensive. The aim of the present study is to assess the usefulness and […]

Exploring tuberculosis by molecular tests on DNA isolated from smear microscopy slides

Tuberculosis (TB) is an infectious disease of global public health importance caused by Mycobacterium tuberculosis complex. The disease has worsened with the emergence of multidrug-resistant (MDR)-TB strains. The timely diagnosis and treatment of TB remains a key public health priority, and laboratories have a critical role in the rapid and accurate detection of TB and […]

Analysing trends and forecasting malaria epidemics in Madagascar using a sentinel surveillance network: a web-based application

Background The use of a malaria early warning system (MEWS) to trigger prompt public health interventions is a key step in adding value to the epidemiological data routinely collected by sentinel surveillance systems. Methods This study describes a system using various epidemic thresholds and a forecasting component with the support of new technologies to improve […]

L’hépatite B toucherait deux fois plus les bébés africains que le VIH

En Afrique subsaharienne, le nombre de nouveau-nés infectés par l’hépatite B serait deux fois plus élevé que par le VIH. Alors que le risque de transmission mère-enfant de l’hépatite B est bien documenté en Asie, les données concernant la situation en Afrique sont encore rares. Dans un article publié dans la revue Alimentary Pharmacology & […]