Durability monitoring of long-lasting insecticidal (mosquito) nets (LLINs) in Madagascar: physical integrity and insecticidal activity

Background Long-lasting insecticidal mosquito nets (LLINs) are highly effective for malaria prevention. However, it is also clear that durability monitoring is essential to predict when, post-distribution, a net population, no longer meets minimum WHO standards and needs to be replaced. Following a national distribution campaign in 2013, we tracked two durability indicators, physical integrity and […]

Plague risk in vulnerable community: assessment of Xenopsylla cheopis susceptibility to insecticides in Malagasy prisons

Background Prisons in Madagascar are at high risk of plague outbreak. Occurrence of plague epidemic in prisons can cause significant episode of urban plague through the movement of potentially infected humans, rodents and fleas. Rodent and flea controls are essential in plague prevention, by reducing human contact with plague reservoirs and vectors. Insecticide treatment is […]

Prevalence of chronic hepatitis B virus infection and infrastructure for its diagnosis in Madagascar

WHO developed a global strategy to eliminate hepatitis B by 2030 and set target to treat 80% of people with chronic hepatitis B virus (HBV) infection eligible for antiviral treatment. As a first step to achieve this goal, it is essential to conduct a situation analysis that is fundamental to designing national hepatitis plans. We […]

Genetic structure and gene flow of the flea Xenopsylla cheopis in Madagascar and Mayotte

We genotyped 205 fleas from 12 sites using nine microsatellite markers. Madagascan populations of X. cheopis differed, with the mean number of alleles per locus per population ranging from 1.78 to 4.44 and with moderate to high levels of genetic differentiation between populations. Three distinct genetic clusters were identified, with different geographical distributions but with […]

Review of Antibiotic Resistance in the Indian Ocean Commission

Review of Antibiotic Resistance in the Indian Ocean Commission: A Human and Animal Health Issue Noellie Gay1*, Olivier Belmonte2, Jean-Marc Collard3, Mohamed Halifa4, Mohammad Iqbal Issack5, Saindou Mindjae6, Philippe Palmyre7, Abdul Aziz Ibrahim7, Harena Rasamoelina8, Loïc Flachet8, Laurent Filleul9 and Eric Cardinale1,8 Antimicrobial resistance (AMR) is a major threat to human, animal health, and environment […]

Seasonal determinants of access to care: implications for measles outbreak risk in Madagascar

Measles containing vaccine was introduced to Madagascar in 1985. Since 2007, intensification of efforts has bought Madagascar closer to the goal of elimination. Nevertheless, recent data also indicate that population immunity might be eroding in the face of high birth rates and barriers to vaccine delivery. Despite evidence that many factors likely to shape vaccination […]

Evaluation of the influenza sentinel surveillance system in Madagascar, 2009–2014

The World Health Organization (WHO) recommends that, from no more than two years after implementation, influenza surveillance systems should be periodically and comprehensively evaluated.1 Such evaluations may enable shortfalls to be identified, performance to be improved and data reliability to be assessed. Although several influenza surveillance systems have been established in Africa,2,3 data on the […]

Usefulness and accuracy of MALDI-TOF mass spectrometry as a supplementary tool to identify mosquito vector species …

Arthropod-borne diseases are important causes of morbidity and mortality. The identification of vector species relies mainly on morphological features and/or molecular biology tools. The first method requires specific technical skills and may result in misidentifications, and the second method is time-consuming and expensive. The aim of the present study is to assess the usefulness and […]