{"id":14356,"date":"2023-11-13T10:25:39","date_gmt":"2023-11-13T07:25:39","guid":{"rendered":"https:\/\/www.pasteur.mg\/?page_id=14356"},"modified":"2025-06-04T14:37:03","modified_gmt":"2025-06-04T11:37:03","slug":"unite-peste","status":"publish","type":"page","link":"https:\/\/www.pasteur.mg\/en\/unites-de-recherche\/unite-peste\/","title":{"rendered":"Unit\u00e9 Peste"},"content":{"rendered":"

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Pr\u00e9sentation<\/h3>\n

[\/et_pb_text][et_pb_divider color=\u00a0\u00bb#000000″ _builder_version=\u00a0\u00bb4.20.4″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb custom_margin=\u00a0\u00bb||0px||false|false\u00a0\u00bb custom_padding=\u00a0\u00bb||0px||false|false\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][\/et_pb_divider][et_pb_text _builder_version=\u00a0\u00bb4.20.4″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb text_font=\u00a0\u00bbFS Joey Light||||||||\u00a0\u00bb text_font_size=\u00a0\u00bb21px\u00a0\u00bb hover_enabled=\u00a0\u00bb0″ inline_fonts=\u00a0\u00bbFS Joey Bold\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb sticky_enabled=\u00a0\u00bb0″]<\/p>\n

L\u2019unit\u00e9 Peste regroupe l\u2019unit\u00e9 de recherche sur la peste et le Laboratoire Central Peste (LCP)<\/a>\u00a0du Minist\u00e8re de la Sant\u00e9 Publique (MinSanP). L\u2019unit\u00e9 assure la confirmation biologique des cas de peste du pays et la surveillance de la sensibilit\u00e9 des souches de Yersinia pestis aux antibiotiques. L\u2019unit\u00e9 dispose d\u2019un plateau technique pour la mise au point et la production des Tests de Diagnostic Rapide (TDR). Le TDR-peste avec son kit de pr\u00e9l\u00e8vement est mis \u00e0 disposition des Services de Sant\u00e9 du District (SSD) et des Centre de Sant\u00e9 de Base (CSB).<\/p>\n

L\u2019unit\u00e9 Peste a \u00e9t\u00e9 nomm\u00e9e Centre Collaborateur de l\u2019Organisation Mondiale de la Sant\u00e9 (CCOMS) pour la lutte et les recherches sur la peste depuis 1998. Elle assure les activit\u00e9s qui r\u00e9pondent aux Termes de R\u00e9f\u00e9rence (ToR) du CCOMS ainsi que des services int\u00e9ressant les programmes d\u2019int\u00e9r\u00eat r\u00e9gional et mondial de l\u2019OMS. Le CCOMS vient en appui aux autres pays dans la r\u00e9gion Africaine (mise \u00e0 disposition de TDR, consultation, confirmation des cas, investigation d\u2019\u00e9pid\u00e9mie et formation).<\/p>\n

Afin de remplir ses missions, l\u2019unit\u00e9 Peste travaille en \u00e9troite collaboration avec d\u2019autres unit\u00e9s de l\u2019IPM telles que l\u2019unit\u00e9 d\u2019Entomologie M\u00e9dicale<\/a>\u00a0pour le volet vecteur, l\u2019unit\u00e9 d\u2019Epid\u00e9miologie et de Recherche Clinique<\/a>\u00a0pour le volet investigation d\u2019\u00e9pid\u00e9mies et la surveillance \u00e9pid\u00e9miologique et l\u2019unit\u00e9 d\u2019Immunologie des Maladies Infectieuses<\/a>\u00a0pour la r\u00e9ponse immune de l\u2019h\u00f4te (homme et rat).<\/p>\n

[\/et_pb_text][et_pb_text _builder_version=\u00a0\u00bb4.20.4″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb header_3_font=\u00a0\u00bbFS Joey Bold||||||||\u00a0\u00bb header_3_text_color=\u00a0\u00bb#107fc3″ header_3_font_size=\u00a0\u00bb30px\u00a0\u00bb custom_margin=\u00a0\u00bb0px||0px||true|false\u00a0\u00bb custom_padding=\u00a0\u00bb0px||0px||true|false\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]<\/p>\n

Axes et projets de recherche<\/h3>\n

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Pour renforcer la lutte contre cette maladie \u00e0 Madagascar, les activit\u00e9s de recherche men\u00e9es par l\u2019unit\u00e9 Peste visent \u00e0 r\u00e9pondre \u00e0 la question : \u00ab Pourquoi la peste persiste-t-elle \u00e0 Madagascar ? \u00bb.<\/p>\n

L\u2019unit\u00e9 s\u2019int\u00e9resse en particulier\u00a0:<\/p>\n

<\/strong>A. Aux caract\u00e9ristiques g\u00e9n\u00e9tiques de l\u2019agent pathog\u00e8ne\u00a0<\/strong><\/p>\n

<\/strong>B. A la r\u00e9ponse de l\u2019h\u00f4te, humain et rongeur, impliqu\u00e9 dans la transmission de la maladie\u00a0<\/strong><\/p>\n

<\/strong>C. \u00c0 l\u2019identification des facteurs de risque et \u00e0 la mod\u00e9lisation de sa transmission\u00a0<\/strong><\/p>\n

<\/strong>D. \u00c0 l\u2019\u00e9valuation d\u2019outils de diagnostic, la d\u00e9termination et\/ou am\u00e9lioration des m\u00e9thodes de lutte contre la peste comme l\u2019\u00e9valuation des candidats vaccins dans le cadre d\u2019\u00e9tude de faisabilit\u00e9 ou \u00ab proof of concept \u00bb\u00a0<\/strong><\/p>\n

 <\/p>\n

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Membres<\/h3>\n

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Les cadres scientifiques<\/strong> :<\/p>\n